PRESTWICK ORIGINAL MOLECULES LIBRARY

Prestwick Original molecules

Your Premium Resource For Novel Screening Hits

A collection of 344 innovative screening compounds, based on selected new original scaffolds, was prepared by Prestwick medicinal chemists. All molecules have been designed to ensure optimal diversity and are suitable for diverse chemical modification yielding analogs with promising IP positions. The library combines favorable drug-like and ADME-Tox properties with high potential therapeutic score.



PRESTWICK CHEMICAL Key features

    PRESTWICK CHEMICAL An original collection of 344 exclusive compounds
    PRESTWICK CHEMICAL Designed considering drug-like properties
    PRESTWICK CHEMICAL Optimal diversity, suitable for multiple chemical modifications
    PRESTWICK CHEMICAL Promising IP positions
    PRESTWICK CHEMICAL Innovative compounds with favorable lead-like (Oprea) and drug-like (Lipinski) properties
    PRESTWICK CHEMICAL Using a structure-based approach (pharmacophore-based virtual screening), each compound was investigated for its potential interactions with protein targets ranging from CNS to oncology, cardiovascular and antimicrobial fields. Target prediction allows to claim that the selected Prestwick Original Molecules (POM) might be active in different therapeutic areas.

PRESTWICK CHEMICALHow provided?

    PRESTWICK CHEMICAL In DMSO at 10 mM (from 100 ┬ÁL up to 1 mL) ready for screening in 96 or 384 well plates. Customized library (volumes, plating) achieved under request
    PRESTWICK CHEMICAL As dry powder in vials starting from 10 mg, with cherry-picking possibility
    PRESTWICK CHEMICAL The database is supplied in three formats (SDF, DB, XLS)
    PRESTWICK CHEMICAL Re-supply of any hit-compound up to 100 mg

PRESTWICK CHEMICALApplications

    PRESTWICK CHEMICAL Small molecule screening
    PRESTWICK CHEMICAL Original starting point in hit/lead discovery programs



sign up to our NEWSLETTER:



No royalties or milestones requested !